For 18 seasons, "South Park" has become known for addressing issues in pop culture and finding a way to spin it into parody. Wednesday night's Season 19 premiere episode, "Stunning and Brave," will keep that tradition alive as Cartman, Kenny, Stan and Kyle will address Tom Brady, his wife Gisele Bündchen and show some respect for Caitlyn Jenner.

In episode 1, the boys will have a new principal in charge of South Park Elementary. According to a South Park Studios press release, he will make the boys face the damage they’ve done "through their history of racism and unconscious bias."

The promo video for the Season 19 premiere shows Cartman taking a dig at the Deflategate scandal, sounding off about how he's going to "pull a Tom Brady" by appealing his four day detention sentence and ask to get no detention at all. The clip can be seen below:

According to The Hollywood Reporter, show creators Matt Stone and Trey Parker are both from Colorado and are fans of the Denver Broncos, so it should come as no surprise that they start the season with a shot at Brady. Brady, who recently had his four game suspension overturned, has been made fun of on "South Park" before.

Brady was shown being unable to control his bladder on the football field in Season 17 episode 5, called "Taming Strange." Kyle's brother Ike was given Tom Brady's hormone pills instead of laxatives by mistake, which the laxatives were sent to Brady.

This will be the second straight year something involving the National Football League will make its way into the season premiere. Season 18 kicked off with an episode called "Go Fund Yourself," where the Washington Redskins organization, including owner Dan Snyder, was mocked for refusing to change their offensive team name. In the episode, the boys start up their own company through Kickstarter and they decide to name their company Washington Redskins because the team no longer had its trademark.

A clip from "Go Fund Yourself," can be seen below:

"South Park" Season 19 premieres Wednesday, Sept. 16 at 10 p.m. EDT on Comedy Central.