Betsy Andreu, the wife of Lance Armstrong’s former teammate Frankie Andreu, appeared on CNN’s “Anderson Cooper 360” immediately after an Oprah Winfrey interview and said, "I'm really disappointed."

"He owed it to me. You owed it to me, Lance, and you dropped the ball,” Andreu continued. "After what you've done to me and my family and you couldn't own up to it. And now we're supposed to believe you?"

Andreu, who became emotional during the interview, said, "You had one chance of the truth, this is it. If he's not going to tell the truth, if he can't say 'yes, the hospital room happened' then how are we to believe everything else he is saying?"

Andreu said she heard Armstrong telling doctors at Indiana University Hospital that he had used performance-enhancing drugs when he was being treated for cancer in 1996, according to a BBC report.

While Armstrong has referred to Betsy Andreu in the past as “crazy,” he told Winfrey that he had apologized to her for that remark. The 41-year-old former cyclist neglected to comment on whether the hospital conversation took place. "I'm not going to take that on," he said.

Furthermore, Armstrong told Winfrey that he was not a fan of the sport’s governing body, the UCI.

In the “AC30” interview, Andreu rejected that, saying: "When he says he doesn't like the UCI, that's a bunch of crap. He had the UCI in his back pocket. Lance wasn't a leader. That's a bunch of crap, because he owned the team. Why did they make sure Frankie's contract wasn't renewed in 2000?"

Andreu also alleged that her husband did not have his contract renewed after refusing to take part in a doping program.

Fallout as a result of the Armstrong/Winfrey interview continued as the United States Anti-Doping Agency has called on Armstrong to admit to the full extent of his use of performance-enhancing drugs under oath.

Following the broadcast of the interview, Usada's chief executive Travis Tygart said in a statement: "Tonight, Lance Armstrong finally acknowledged that his cycling career was built on a powerful combination of doping and deceit.

"His admission that he doped throughout his career is a small step in the right direction. But if he is sincere in his desire to correct his past mistakes, he will testify under oath about the full extent of his doping activities."

In November 2012, Armstrong stood down as chairman of the Lance Armstrong Foundation, known as Livestrong, in an effort to “spare the foundation any negative effects as a result of controversy surrounding” his situation.

"We at the Livestrong Foundation are disappointed by the news that Lance Armstrong misled people during and after his cycling career, including us," a recent statement from the charity read.

"Earlier this week, Lance apologised to our staff and we accepted his apology in order to move on and chart a strong, independent course.

"We look forward to devoting our full energy to our mission of helping people not only fight and survive cancer, but also thrive in life after cancer.

"Even in the wake of our disappointment, we also express our gratitude to Lance as a survivor for the drive, devotion and spirit he brought to serving cancer patients and the entire cancer community.

"Lance is no longer on the foundation's board, but he is our founder and we will always be grateful to him for creating and helping to build a foundation that has served millions struggling with cancer.

"Our success has never been based on one person – it's based on the patients and survivors we serve every day, who approach a cancer diagnosis with hope, courage and perseverance.

"They have been, are and always will be our focus."

Further comments from those close to Armstrong included Britain's former Olympic champion Nicole Cooke.

After Armstrong claimed he only doped to create "a level playing field," Cooke told BBC Radio Five Live: "If he was trying to convince himself by arguments like that, he's got no morals – he is a disgusting human being.

"The sad thing is that there were clean riders who had livelihoods, whole careers stolen from them by that. We're probably not going to see those people vindicated in any way through this.

"I don't think he grasps the scale of what he's done and its impact on so many people."

Cooke insisted there are still questions to answer about Armstrong's doping and the other parties involved.

"I think we still need to get to the bottom of the Lance Armstrong fraud," she said.

"Floyd Landis [who was also stripped of a Tour title] said that he was able to cover up his positive tests with officials and we really need to find out the answer to those questions. We're close to the bottom but we still need to uncover the last few things."