Senate Democrats are vowing to vote on President Joe Biden’s $1.75 trillion Build Back Better Bill despite Sen. Joe Manchin, D-W. Va., voicing his opposition to the president’s plan to expand social safety net programs and combat climate change.

"The Senate will, in fact, consider the Build Back Better Act, very early in the new year so that every Member of this body has the opportunity to make their position known on the Senate floor, not just on television," Senate Majority Leader Chuck Schumer, D-N.Y., wrote in a letter to his colleagues.

In order to pass the second half of Biden’s agenda, all 50 Senate Democrats would be needed to get the bill to his desk, and Manchin’s newly voiced opposition is the death blow to Biden’s agenda after months of negotiations watering the bill down to appease the West Virginia senator.

“I cannot vote to continue with this piece of legislation. I just can’t,” Manchin told “Fox News Sunday.” “I’ve tried everything humanly possible. I can’t get there.”

The bill would have extended the child tax credit of up to $300 per child a month, expanded Medicare and Medicaid, provided child care services and incentivized green energy. Schumer said the Senate will vote on a “revised House version” of Build Back Better until something gets done.

Many Democrats view passing the legislation as vital for the party to keep its razor-thin majority in the House as well as their control of the deadlocked Senate during the 2022 midterms, and failing to do so will result in a 2010 Tea Party-style bloodbath.

White House Press Secretary Jen Psaki addressed Manchin’s unwillingness to vote for the bill, saying he “reversed his position” on Build Back Better, adding “we will continue to press him to see if he will reverse his position yet again, to honor his prior commitments and be true to his word.” She noted the fight for Build Back Better is “too big to give up.”