Lance Armstrong’s highly talked-about interview with talk show queen Oprah Winfrey is airing Thursday night on OWN network.

The interview is the first of a two-night, worldwide exclusive interview that can be viewed by live stream.

The no-holds-barred interview is going to be watched by many as Armstrong reveals that he used performance-enhancing drugs.

After the interview, which was taped in Austin, Texas, Winfrey tweeted on Monday:

"Just wrapped with @lancearmstrong More than 2 1/2 hours. He came READY!"

The athlete will be discussing his doping scandal, all of the years he was accused of cheating and charges regarding him lying about using performance-enhancing drugs throughout his entire cycling career, according to OWN.

Winfrey speaks with Armstrong for the first time since he was stripped of his seven Tour de France wins and thusly losing millions of dollars’ worth of endorsement deals after he was investigated by the U.S. Anti-Doping Agency.

The federal agency released an extensive report that accused the cyclist of doping through his entire career.

As a result, Armstrong received a lifetime ban from competing professionally. Following the news, the athlete and cancer survivor stepped down as the chairman from the foundation he started, Livestrong, which helped raised millions of dollars to help fight cancer.

People took to the Twitterverse to discuss cutting their Livestrong bracelets, the yellow band that simply read “Livestrong.”

Others mocked the cyclist and his confession, with one user saying, “Following up Lance Armstrong's confession, next week Oprah is going to interview Sir Mix-A-Lot who will reveal he actually likes small butts.”

Time magazine published an article with the headline, “Who Cares If Lance Armstrong Is Sorry?”

Armstrong hasn’t responded to any of the negative comments on his personal Twitter account, with his last post being a retweet of Winfrey saying she was excited for their conversation before the interview had taken place.

Don’t miss the exclusive interview premiering on Thursday night at 9 p.m. EST on OWN and the second part on Friday at the same time.