U.S. President Barack Obama delivers remarks at the My Brother's Keeper Summit at the South Court Auditorium of the White House in Washington, Dec. 14, 2016. Reuters

President Barack Obama will hold his final news conference of the year Friday at the White House at 2:15 p.m. EST. Following the conference, Obama and his family will leave for their annual vacation in Hawaii, the White House said Thursday.

According to reports, Obama is likely to address everything from Russian hacking to the crisis in the Syrian city of Aleppo. He is also expected to speak about Donald Trump's presidency, which will start Jan. 20, and Trump's cabinet picks.

The conference will be live streamed on the White House website here, below and on major news networks.

On Thursday, Obama told NPR in an exclusive interview that the U.S. will definitely "take action" against Russia for reportedly launching cyberattacks and trying to influence the presidential election.

"I think there is no doubt that when any foreign government tries to impact the integrity of our elections ... we need to take action," Obama told Steve Inskeep, the host of NPR's "Morning Edition" program. "And we will — at a time and place of our own choosing. Some of it may be explicit and publicized; some of it may not be."

The White House announced Thursday that the Obamas were slated to leave about three hours after the press conference. They will travel via Marine One, en route to Andrews Air Force Base, to board Air Force One for the overnight flight to Hawaii to begin their 15-day break.

Once there, the family will participate in no public events except for Obama's meeting with Japanese Prime Minister Shinzo Abe, according to an advisory. However, pool reporters will cover the trip.

The Obamas also traveled to Hawaii last year in December, spending at least $4.8 million for the vacation trip, the Judicial Watch recently reported, citing records from the U.S. Secret Service.