Andrew Luck Indianapolis Colts
There's a chance Andrew Luck won't be able to play in Week 4. Getty

Week 4 began with the Baltimore Ravens defeating the Pittsburgh Steelers 23-20 in overtime, forcing a push of the three-point betting line. Baltimore had been favored by 2.5 points at the start of the week, and a few other point spreads have changed in the last few days, as well.

The biggest change comes in the Sunday afternoon game between the Indianapolis Colts and Jacksonville Jaguars. Once nine-point favorites across the board, the Colts have become seven or eight-point favorites at some sportsbooks. Other Las Vegas casinos have taken the betting odds off the board altogether, because the status of Andrew Luck is now uncertain. The quarterback is dealing with a shoulder injury, and he’s questionable for the Week 4 contest after missing Friday’s practice.

The Buffalo Bills were six-point favorites at home over the New York Giants, but the betting line has moved to five points. Wide receiver Sammy Watkins and running back LeSean McCoy have both been ruled out for Sunday’s game. Giants wide receiver Victor Cruz will sit as well, even though it was assumed that he’d make his 2015 season debut in Week 4.

The Seattle Seahawks are the biggest favorites of the week, and the point spread in their game with the Detroit Lions has moved from 9.5 to 10 points. The undefeated Green Bay Packers have gone from nine-point favorites to 8.5-point favorites over the San Francisco 49ers.

Many sportsbooks don’t have a betting line for the Dallas Cowboys’ visit to New Orleans. Tony Romo is out, but Drew Brees’ status is uncertain.

Below are updated betting lines for all the Week 4 games ahead of the weekend. These are the consensus odds from multiple sportsbooks in Las Vegas, via

New York Jets (-1.5) at Miami Dolphins, 42

Houston Texans (+6.5) at Atlanta Falcons, 46.5

Carolina Panthers (-3) at Tampa Bay Buccaneers, 40

New York Giants (+5) at Buffalo Bills, 46

Oakland Raiders (-3) at Chicago Bears, 44.5

Philadelphia Eagles (-3) at Washington Redskins, 43.5

Kansas City Chiefs (+4) at Cincinnati Bengals, 45

Cleveland Browns (+7.5) at San Diego Chargers, 45

Green Bay Packers (-8.5) at San Francisco 49ers, 48.5

Minnesota Vikings (+7) at Denver Broncos, 43

St. Louis Rams (+7) at Arizona Cardinals, 42.5

Dallas Cowboys (+4) at New Orleans Saints, 46.5

Detroit Lions (+10) at Seattle Seahawks, 43